Most played cards in Life:

3 Decks
Benevolent Bodyguard
12 copies - 4 average
Commune with the Gods
12 copies - 4 average
Presence of Gond
12 copies - 4 average
Battle Screech
12 copies - 4 average
Soul's Attendant
12 copies - 4 average
Midnight Guard
12 copies - 4 average
Soul Warden
12 copies - 4 average
Pyroblast
10 copies - 3.33 average
Spidersilk Armor
9 copies - 3 average
Khalni Garden
9 copies - 3 average
Oblivion Ring
9 copies - 3 average
Ash Barrens
9 copies - 3 average
Blossoming Sands
9 copies - 3 average
Prismatic Strands
9 copies - 3 average
Journey to Nowhere
8 copies - 2.67 average
Wind-Scarred Crag
6 copies - 2 average
Faerie Macabre
6 copies - 2 average
Survivors' Encampment
6 copies - 2 average
Cenn's Enlistment
6 copies - 2 average
Rally the Peasants
6 copies - 2 average